【Description】White or almost white, hygroscopic powder
【Pharmacological Action】
Colistin (Polymyxin E) is polymyxin antibiotic produced by culture of Bacillus polymyxa var colistinus. It is effective primarily against gram-negative microorganisms such as E-coli and Salmonella. Colistin is bactericidal and it causes disorganisation of the bacterial cell membrane with leakage of intracellular materials and inhibits bacterial oxidative metabolism. Gram-positive bacteria are naturally resistant to colistin. However, acquired resistance of gram-negative enteric bacteria to colistin is uncommon.
In the target species, colistin sulfate is very poorly absorbed after oral administration. Plasma concentrations after oral administration are generally undetectable. Orally administered colistin is excreted in the faeces.
【Indication】 Prevention and treatment of infections of the gastrointestinal tract caused by gram-negative microorganisms susceptible to colistin.
【Caution】Do not feed to layer in laying period.
【Storage】Keep in tight, light-resistant container. Seal the bag after use.
【Specification】EP standard
【Package】20kg/Carton
【Retest Date】Three Years